Bent Penis

Also known as Peyronie’s disease

Erectile dysfunction (ED) is a condition in which a person with a penis has difficulty getting or maintaining an erection. It can cause problems in the bedroom for people of all ages. One rare form of ED, called Peyronie’s disease, results in a bend in the penis that can make an erection painful. 

While a curved erection doesn’t always indicate a problem, people who have Peyronie’s disease may have trouble having sex. This often causes anxiety and discomfort. Keep reading to understand more about Peyronie’s disease.

Causes of Peyronie’s disease

According to the Mayo Clinic, the cause of Peyronie’s disease is largely unknown. However, research suggests that the condition may develop after trauma to the penis, such as bending or hitting. This can cause bleeding and subsequent scar tissue buildup.

While injury may be the cause of the condition in some cases, the National Kidney and Urologic Diseases Clearinghouse (NKUDC) notes that often the condition arises without a traumatic event.

Risk factors of Peyronie’s disease

Genetics and age appear to play a role in Peyronie’s disease. The condition can be genetic and run in families, giving some people a genetic predisposition.

Tissue changes lead to easier injury and slower healing as people get older. This puts them at greater risk for developing the condition.

Those with a connective tissue disorder called Dupuytren’s contracture have a higher chance of developing Peyronie’s disease. Dupuytren’s contracture is a thickening in the hand that makes your fingers pull inward.

Symptoms of Peyronie’s disease

The main symptom of Peyronie’s disease is the formation of flat scar tissue called plaque. This scar tissue can generally be felt through the skin. Plaque normally forms on the top side of the penis but may also occur on the bottom or side. 

Sometimes plaque goes all the way around the penis, causing a “waisting” or “bottleneck” deformity. Plaque may gather calcium and become very hard. Scar tissue might cause painful erections, soft erections, or severe curvature.

Scar tissue on a certain part of the penis reduces elasticity in that area. Plaque on the top of the penis may cause it to bend upward during an erection. Plaque on the side may cause curvature toward that side. More than one plaque can cause complex curvatures.

Curvature may make sexual penetration more difficult. Scar tissue may cause shrinkage or shortening of the penis.

Tests and diagnosis

If you think you have Peyronie’s disease, the first step is to visit your primary doctor. A physical exam helps your doctor determine whether you have the condition. This exam may involve taking an initial measurement of your penis.

By measuring the penis, your doctor can identify the location and amount of scar tissue. This also helps determine whether your penis has shortened. Your doctor may also suggest an ultrasound to reveal the presence of scar tissue, and they may refer you to a urologist.

Treatment for Peyronie’s disease

There’s no cure for Peyronie’s disease, but it’s treatable and may go away on its own. Though it may be tempting to request medication right away, many doctors prefer the “watchful waiting” approach if your symptoms aren’t severe.

Medication

Your doctor may recommend medications — often drugs injected into the penis — or even surgery if you’re experiencing more pain or penis curvature over time.

Only one medication, clostridium hystolyticum (Xiaflex), is approved by the Food and Drug Administration (FDA) to treat the condition. It’s approved for use in people whose penis curves more than 30 degrees during erection.

The treatment involves a series of penile injections that break down the buildup of collagen.

Two other types of medicines that may be prescribed are:

Nonsurgical options

Nondrug treatments are being investigated, such as:

  • shockwave therapy to break up scar tissue
  • penile traction therapy to stretch the penis
  • vacuum devices

People being treated with Xiaflex may benefit from gentle penile exercises. For 6 weeks after treatment, you should do two activities:

  • Stretch the penis when not erect, three times daily for 30 seconds per stretch.
  • Straighten the penis when experiencing a spontaneous erection unrelated to sexual activity for 30 seconds, once daily.
Lifestyle changes

Lifestyle changes may reduce the risk of ED related to Peyronie’s disease. These include:

Surgery

Surgery is the last course of action in the case of severe penis deformity. According to the NKUDC, you should wait at least 1 year before turning to surgery for Peyronie’s disease. Surgical solutions include:

  • shortening the unaffected side
  • lengthening the scar tissue side
  • penile implants

Lengthening runs a greater risk of erectile dysfunction. Shortening the unaffected side is used when curvature is less severe.

One type of shortening is a procedure called the Nesbit plication. In this procedure, doctors remove or cinch excess tissue on the longer side. This creates a straighter, shorter penis.

Natural remedies

Most natural remedies for Peyronie’s disease aren’t well-studied and are based on anecdotal evidence. A couple remedies have been studied and show promise. However, American Urological Association guidelines stress that the evidence is insufficient to recommend their use.

A 2001 study published in BJU International concluded that acetyl-l-carnitine “is significantly more effective and safe than tamoxifen in treating acute and early chronic Peyronie’s disease.” No follow-up study has been published. 

Results of a 2010 study published in International Journal of Impotence Research found that coenzyme Q10 supplements improves erectile function. They also reduced penile curvature in patients with early chronic Peyronie’s disease. More study is needed. 

According to an article published in Reviews in Urology, vitamin E has been extensively studied for treating Peyronie’s disease. Recent studies show no improvement in patients treated with vitamin E compared to placebo.

Peyronie’s disease in young people

Peyronie’s disease is most common in middle-aged people but may occur in those as young as 20. Research shows 8 to 10 percent of those with Peyronie’s disease are under the age of 40. 

Most young people with Peyronie’s present with symptoms such as painful erection. They often require medical intervention due to acute disease. Less than 21 percent of patients researched had a history of erectile dysfunction.

Complications

In addition to the anxiety or stress the condition may cause you — and perhaps your partner — other complications may arise. Difficulty achieving or keeping an erection makes it difficult to have sexual intercourse. 

If intercourse isn’t possible, you may be unable to conceive a child. Seek support from your healthcare team, which may include your doctor, and a psychological counselor, to help you face these complex issues.

Talking to your partner

This type of anxiety may lead to problems with your sexual partner.

Take steps to nip stress in the bud. Talk to your partner about Peyronie’s disease and how it may affect your performance in bed. If necessary, enlist the support of your doctor or a therapist to help you manage. 

Bottom Line:

Research is underway to help scientists better understand what causes Peyronie’s disease. Researchers hope their investigation into the process will lead them to an effective therapy to help people with Peyronie’s disease.

In the meantime, do what you can to understand the condition and take necessary steps to improve your quality of life — both in and outside of the bedroom.

Reference:
https://www.healthline.com/reviewers/matt-coward-md-facs
https://www.healthline.com/authors/-560
About verapamil injections for treatment of Peyronie's disease. (2019).
org/cancer-care/patient-education/about-penile-injections-verapamil
Biagiotti G, ete al. (2001). Acetyl-l-carnitine vs tamoxifen in the oral therapy of Peyronie’s disease: A preliminary report.
wiley.com/doi/10.1046/j.1464-410x.2001.02241.x/abstract;jsessionid=6DB2B2969E95E49D863275BFCB00632A.f04t03
How does XIAFLEX®work? (n.d.).
peyronies-disease.xiaflex.com/hcp/about-xiaflex/
Kuehhas FE, et al. (2011). Peyronie’s disease: Nonsurgical options.
nlm.nih.gov/pmc/articles/PMC3221554/
Mayo Clinic Staff. (2020). Peyronie’s disease.
org/diseases-conditions/peyronies-disease/symptoms-causes/syc-20353468
Nehra A, et al. (2015). Peyronie's disease: AUA guideline.
org/documents/education/clinical-guidance/Peyronies-Disease.pdf
Penile curvature (Peyronie's disease). (2020).
nih.gov/health-information/urologic-diseases/penile-curvature-peyronies-disease
Peyronie’s disease. (2020).
org/urology-a-z/p/peyronies-disease
Peyronie’s disease. (n.d.).
weillcornell.org/peyronies-disease
Safarinejad, MR. (2010). Safety and efficacy of coenzyme q10 supplementation in early chronic peyronie’s disease: A double-blind, placebo-controlled randomized study.
com/articles/ijir201020
Tefekli A, et al. (2001). Peyronie’s disease in men under 40: Characteristics and outcome.
com/articles/3900635
Photo Credit: Deon Black

コメントを残す